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Publication From 2005
Original, peer reviewed articles

  • *Kaufmann P, Levy G, Thompson JLP, DelBene ML, Battista V, Gordon P, Rowland LP, Levin B, Mitsumoto H. The ALSFRSr predicts survival time in an ALS clinical population. Neurology 2005;64:38-43.

  • Scelsa SN, MacGowan DJ, Mitsumoto H, et al. A pilot, double-blind, placebo-controlled trial of indinavir in patients with ALS. Neurology 2005; 64:1298-300.

  • Albert SM, Rabkin JG, Del Bene ML, Tider T, O’Sullivan I, Rowland LP, Mitsumoto H. Wish to die in end-stage ALS. Neurology 2005;65:68-74 (With the editorial comments).

  • Rabkin J, Albert S, Del Bene M, O’Sullivan I, Tider T, RowlandLP, Mitsumoto H. Prevalence of depressive disorders and change over time in late-stage ALS. Neurology 2005:65: 62-67 (With the editorial comments).

  • Mitusmoto H, Bromberg M, Johnston W, et al. Promoting excellence in end-of-life care in ALS. ALS and Other MND 2005;6:145-154.

  • Li X, Rowland LP, Mitsumoto H, Przedborski S, Bird TD, Schellenberg GD, Peskind E, Johnson N, Siddique T, Mesulam MM, Weintraub S, Mastrianni JA. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Ann Neurol. 2005;58:858-864.

  • Gordon PH, Cheng B, Katz IB, Pinto M, Hays AP, Mitsumoto H, Rowland LP. The natural history of primary lateral sclerosis. Neurology. 2006;66:647-653.

  • Levy G, Kaufmann P, Buchsbaum R, Montes J, Barsdorf A, Arbing A, Battista V, Zhou X, Mitsumoto H, Levin B, Thompson JLP. A two-stage design for a phase II clinical trial of coenzyme Q10 in ALS. Neurology 2006;66:660–663.

  • Rippon GA, Scarmeas N, Gordon PH, Murphy PL, Albert SM, Mitsumoto H, Marder K, Rowland LP, Stern Y. An observational study of cognitive impairment in amyotrophic lateral sclerosis. Arch Neurol. 2006;63:345-52.

  • Gordon PH, Doorish C, Montes J, Mosley RL, Diamond B, MacArthur RB, Weimer LH, Kaufmann P, Hays AP, Rowland LP, Gendelman HE, Przedborski S, Mitsumoto H. Randomized controlled phase II trial of glatiramer acetate in amyotrophic lateral sclerosis. Neurology 2006;66:1117-1119.

  • Hays AP, Naini A, He CZ, Mitsumoto H, Rowland LP. Sporadic amyotrophic lateral sclerosis and breast cancer: Hyaline conglomerate inclusions lead to identification of SOD1 mutation. J Neurol Sci 2006;242:67-9.

  • Mitsumoto H, Floyd A, Tang MX, Kaufmann P, Battista V, Hristova A, Pullman SL. Transcranial magnetic stimulation for upper motor neuron involvement in amyotrophic lateral sclerosis (ALS). Suppl Clin Neurophysiol. 2006;59:327-32.

  • Rabkin JG, Albert SM, Tider T, Del Bene ML, O'Sullivan I, Rowland LP, Mitsumoto H. Predictors and course of elective long-term mechanical ventilation: A prospective study of ALS patients. Amyotroph Lateral Scler. 2006;7:86-95.

  • *Montes J, Levy G, Albert S, Kaufmann P, Buchsbaum R, Gordon PH, Mitsumoto H. Development and Evaluation of a Self-Administered Version of the ALSFRS-R. Neurology 2006;67:1294-6.

  • Kaufmann P, G Levy, J Montes, R Buchsbaum, MA Barsdorf, V Battista, R Arbing, P H Gordon, H Mitsumoto, BE Levin and JLP Thompson. Excellent inter-rater, intra-rater, and telephone-administered reliability of the ALSFRS-R in a multicenter clinical trial. Amyotroph Lateral Scler 2007;8:42-6.

  • Lange DJ, Lechtzin N, Davey C, David W, Heiman-Patterson T, Gelinas D, Becker B, Mitsumoto H; HFCWO Study Group. High-frequency chest wall oscillation in ALS: an exploratory randomized, controlled trial. Neurology. 2006;67(6):991-7.

  • Kaufmann P, Mitsumoto H; ALSRG Database Task Force Steering Committee; ALSRG Members. ALS Research Group (ALSRG): second meeting, a summary report.
    Amyotroph Lateral Scler 2006;7:252-5.

  • Whittle AJ, Ross OA, Naini A, Gordon P, Mistumoto H, Dachsel JC, Stone JT, Wszolek ZK, Farrer MJ, Przedborski S. Pathogenic Lrrk2 substitutions and Amyotrophic lateral sclerosis. J Neural Transm 2007;114:327-9.

  • Lechtzin N, Lange DJ, Davey C, Becker B, Mitsumoto H. Measures of dyspnea in patients with amyotrophic lateral sclerosis. Muscle Nerve 2007;35:98-102.

  • Mitsumoto H, Uluğ AM, Pullman SL, et al. Quantitative Objective Markers for Upper and Lower Motor Neuron Dysfunction in Amyotrophic Lateral Sclerosis. Neurology 2007;17:1402-1410.

  • * Dal Bello-Haas V, Florence JM, Kloos AD, Scheirbecker J, Lopate G, Hayes SM, Pioro EP, Mitsumoto H. A Randomized Controlled Trial of Resistance Exercise in Individuals with ALS. Neurology 2007;68:2003-2007.

  • Naini A, Mehrazin M, Lu J, Gordon P, Mitsumoto H. Identification of a novel D109Y mutation in Cu/Zn superoxide dismutase (sod1) gene associated with amyotrophic lateral sclerosis. J Neurol Sci 2007;254:17-21.

  • Mitsumoto H, Rabkin JG. Palliative Care for Patients with amyotrophic lateral sclerosis. “Prepare for the worst and hope for the best.” JAMA 2007;298: 207-216.

  • Mosley RL, Gordon PH, Hasiak CM, Van Wetering FJ, Mitsumoto H, Gendelman HE. Glatiramer acetate immunization induces specific antibody and cytokine responses in ALS patients. Amyotroph Lateral Scler 2007; 8:235-42.

  • Dunckley T, Huentelman MJ, Craig DW, Pearson JV, Szelinger S, Joshipura K, Halperin RF, Stamper C, Jensen KR, Letizia D, Hesterlee SE, Pestronk A, Levine T, Bertorini T, Graves MC, Mozaffar T, Jackson CE, Bosch P, McVey A, Dick A, Barohn R, Lomen-Hoerth C, Rosenfeld J, O'connor DT, Zhang K, Crook R, Ryberg H, Hutton M, Katz J, Simpson EP, Mitsumoto H, Bowser R, Miller RG, Appel SH, Stephan DA. Whole-Genome Analysis of Sporadic Amyotrophic Lateral Sclerosis. N Engl J Med. 2007;357:775-88.

  • Miller R, Bradley W, Cudkowicz M, Hubble J, Meininger V, Mitsumoto H, Moore D, Pohlmann H, Sauer D, Silani V, Strong M, Swash M, Vernotica E, TCH346 Study Group. Phase II/III randomized trial of TCH346 in patients with ALS. Neurology 2007;69:776-84.

  • Montes, J., Cheng, B., Diamond, B., Doorish, C., Mitsumoto,H. and Gordon, P. H. The Timed Up and Go test: Predicting falls in ALS. Amyotrophic Lat Scler 2007; 8:292-295.

  • Radunovic A, Mitsumoto H, Leigh PN. Clinical care of patients with amyotrophic lateral sclerosis. Lancet Neurol 2007;6:913-25.

  • Gordon PH, Cheng B, Montes J, Doorish C, Albert SM, Mitsumoto H. Outcome measures for early phase clinical trials. Amyotroph Lateral Scler 2007;8:270-273.

  • Gordon PH, Wang Y, Doorish C, Lewis M, Battista V, Mitsumoto H, Marder K. A screening assessment of cognitive impairment in patients with ALS. Amyotroph Lateral Scler. 2007;8;362-365.

  • Gordon PG, Moore DH, Miller RG, Florence JM, Verheijde JL, Doorish C, Hilton JF, Spitalny GM, MacArthur RB, Mitsumoto H, et al. Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial. Lancet Neurol 2007; 6:1045-53.

  • Gwinn K, Corriveau RA, Mitsumoto H, et al. Amyotrophic Lateral Sclerosis: An Emerging Era of Collaborative Gene Discovery. PloS ONE 2007;1:e1254.

  • de Carvalho M, Dengler R, Eisen A, England JD, Kaji R, Kimura J, Mills K, Mitsumoto H, Nodera H, Shefner J, Swash M. Electrodiagnostic criteria for diagnosis of ALS. Consensus of an International Symposium sponsored by IFCN, December 3-5 2006, Awaji-shima, Japan. Clin Neurophysiol 2008;119:493-503.

  • Mitsumoto H, Santella RM, Liu X, Bogdanov M, Zipprich J, Wu H-C, Mahata J, Kilty M, Bednarz K, Bell D, Gordon PH, Hornig M, Mehrazin M, Naini A, M. Beal MF, Factor-Litvak P. Oxidative Stress Biomarkers in Sporadic ALS. Amyotroph Lateral Scler 2008; 9:177-83.

  • Chen A, Montes J, Mitsumoto H. The Role of Exercise in Amyotrophic Lateral Sclerosis. Phys Med Rehabil Clin N Am. 2008;19:545-557.

  • Gordon PH, Cheung YK, Levin B, et al (Mitsumoto H, 14/29 authors). A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. Amyotroph Lateral Scler. 2008; 9:212-22.

  • Dimos JT, Rodolfa KT, Niakan KK, Weisenthal LM, Mitsumoto H, Chung W, Croft GF, Saphier G, Leibel R, Goland R, Wichterle H, Henderson CE, Eggan K. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008; 321:1218-21.

  • Rutherford NJ, Zhang YJ, Baker M, Gass JM, Finch NA, Xu YF, Stewart H, Kelley BJ, Kuntz K, Crook RJ, Sreedharan J, Vance C, Sorenson E, Lippa C, Bigio EH, Geschwind DH, Knopman DS, Mitsumoto H, Petersen RC, Cashman NR, Hutton M, Shaw CE, Boylan KB, Boeve B, Graff-Radford NR, Wszolek ZK, Caselli RJ, Dickson DW, Mackenzie IR, Petrucelli L, Rademakers R. Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis. PLoS Genet. 2008;4:e1000193.
Book Chapters
  • Rowland LP, Mitsumoto H, De Vivo DC. Hereditary and acquired motor neuron diseases. In Rowland LP (ed): Merritt’s Neurology. 11th edition. Lippincott Williams and Wilkins. Baltimore, 2005; 861-869.

  • Murray B, Mitsumoto H. The spectrum of motor neuron disorders. In Brown RH Jr, Swash M, Pasinelli P (eds). Amyotrophic Lateral Sclerosis. Informa, London, 2006;3-24.

  • Gordon PH, Mitsumoto H. Symptomatic therapy and palliative aspects of clinical care. In Eisen AA, Shaw PJ (eds). Motor Neuron Disorders and Related Diseases. Handbook of Clinical neurology. 2007; 82:389-424.

  • Murray B, Mitsumoto H. Disorders of Upper and Lower Motor Neuron Diseases (Chapter 78). In Bradley WG, Daroff RB, Fenichel GM, Jankovic J., Eds. Neurology in clinical Practice 5th Edition. 2008; 2183-2220.

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Last updated: February 6, 2014 | Comments
ALS Center Neurology, Columbia University CUMC